Dr Khoza holds many distinguished directorships, which include being the Founding Chairman of AKA Capital, the Chairman of Nedbank and the NEPAD Business Foundation, Polokwane International Airport, and Akani Leisure (Pty) Limited and Aka Resources Holdings.

He currently holds directorships at the JSE Securities Exchange, Corobrik (Pty) Limited, Protea Hospitality Limited, Gold Reef Casino Resorts Limited.

Furthermore, Dr Khoza is a leading proponent of a new management culture and leadership based on inclusively, Afrocentricity and Ubuntu. As an advocate of African-led globally competitive economics and industries from the mother continent, he is a distinguished consultant, lecturer, and has been an active change agent in the business community for the past three decades.

Currently Dr Khoza is a Fellow and President of the Institute of Directors in Southern Africa, an Executive Committee Member of the World Business Council for Sustainable Development, and Member of International Business Council of the World Economic Forum. He is also a member and past director and patron of the Black Management Forum (BMF), a former council member of the South African Institute of Management, and a member of the Strategic Management Society of Southern Africa.

In recognition of his leadership skills, he was the recipient of the 2001 Leadership in Practice Award from the University of South Africa (UNISA) – School of Business Leadership, the 2000 Excellence in Business Management Award from the University of the North, and the 1997 Black Management Forum (BMF) Presidential Achievers Award.

His previous Chairmanships include Eskom, Co-ordinated Network Investments, Tolcon, Vodac, South African Student Internship Foundation, Sun Air, Corridor Development Corporation, Creda Press, Glaxo-Smith Kline.

His previous Directorships include Co-ordinated Management Consulting, Munich Reinsurance SA, S C Johnson & Son SA, Servgro, Vodacom Group, JCI, Pinnacle Holdings, IBM SA, IST Holdings, Datacentrix, Guardrisk Assurance Co Ltd., Norwich Holdings, Norwich Life, Comair Ltd., Standard Bank Group Ltd., Standard Bank of South Africa, Liberty Group Ltd.